Selected Papers 2010
Besche V, Wiechmann N, Castor T, Trojandt S, Höhn Y, Kunkel H, Grez M, Grabbe S, Reske-Kunz AB, Bros M. Dendritic cells lentivirally engineered to overexpress interleukin-10 inhibit contact hypersensitivity responses, despite their partial activation induced by transduction-associated physical stress.J Gene Med. 2010;12(3):231-43.
»PubMed
Kuçi S, Kuçi Z, Kreyenberg H, Deak E, Pütsch K, Huenecke S, Amara C, Koller S, Rettinger E, Grez M, Koehl U, Latifi-Pupovci H, Henschler R, Tonn T, von Laer D, Klingebiel T, Bader P. CD271 antigen defines a subset of multipotent stromal cells with immunosuppressive and lymphohematopoietic engraftment-promoting properties. Haematologica 2010; 95(4):651-9.
»PubMed
Stein S, Ott MG, Schultze-Strasser S, Jauch A, Burwinkel B, Kinner A, Schmidt M, Krämer A, Schwäble J, Glimm H, Koehl U, Preiss C, Ball C, Martin H, Göhring G, Schwarzwaelder K, Hofmann WK, Karakaya K, Tchatchou S, Yang R, Reinecke P, Kühlcke K, Schlegelberger B, Thrasher AJ, Hoelzer D, Seger R, von Kalle C, Grez M. Genomic instability and myelodysplasia with monosomy 7 consequent to EVI1 activation after gene therapy for chronic granulomatous disease. Nat Med. 2010;16(2):198-204.
»PubMed
Loew R, Meyer Y, Kuehlcke K, Gama-Norton L, Wirth D, Hauser H, Stein S, Grez M, Thornhill S, Thrasher A, Baum C, Schambach A. A new PG13-based packaging cell line for stable production of clinical-grade self-inactivating gamma-retroviral vectors using targeted integration. Gene Ther. 2010; 17(2):272-80.
»PubMed
Vogler I, Newrzela S, Hartmann S, Schneider N, von Laer D, Koehl U, Grez M. An Improved Bicistronic CD20/tCD34 Vector for Efficient Purification and In Vivo Depletion of Gene-Modified T Cells for Adoptive Immunotherapy. Mol Ther. 2010; 18(7):1330-8.
»PubMed
Vafaizadeh V, Klemmt P, Brendel C, Weber K, Doebele C, Britt K, Grez M, Fehse B, Desriviéres S, Groner B. Mammary epithelial reconstitution with gene-modified stem cells assigns roles to Stat5 in luminal alveolar cell fate decisions, differentiation, involution, and mammary tumor formation. Stem Cells. 2010; 28(5):928-38.
»PubMed
Tabatabai G, Hasenbach K, Herrmann C, Maurer G, Möhle R, Marini P, Grez M, Wick W, Weller M. Glioma tropism of lentivirally transduced hematopoietic progenitor cells. Int J Oncol. 2010; 36(6):1409-17.
»PubMed
Wichmann C, Becker Y, Chen-Wichmann L, Vogel V, Vojtkova A, Herglotz J, Moore S, Koch J, Lausen J, Mäntele W, Gohlke H, Grez M. Dimer-tetramer transition controls RUNX1/ETO leukemogenic activity. Blood. 2010; 116(4):603-13.
»PubMed
Wichmann C, Grez M, Lausen J. Molecular Targeting of Aberrant Transcription Factors in Leukemia: Strategies for RUNX1/ETO. Curr Drug Targets 2010 [Epub]
»PubMed
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