kein Gastseminar

kein Gastseminar

Prof. Dr. Andreas Herrlich
Harvard Medical School
Boston, USA

Prof. Dr. Robert Fürst
Institut für Pharmazeutische Biologie
Goethe-Universität Frankfurt

Prof. Dr. Jörn Walter
Universität des Saarlandes
Saarbrücken

Prof. Dr. Hansjörg Schild
Institute for Immunology
University Medical Center Mainz

Prof. Dr. Manfred Jung
Albert-Ludwigs-Universität
Freiburg

Prof. Dr. Tom Milne
University of Oxford

Winterschule des GK 1172

Dr. Roland Buelow
OMNIRAT
Palo Alto
USA

Prof. Dr. Andreas Plückthun
Universität Zürich

Dr. Thomas Schatton
Harvard Medical School
Boston, USA

Prof. Dr. Wolfgang Uckert
MDC Berlin

Prof. Dr. Veit Hornung
Institut für Klinische Chemie und Pharmakologie
Universitätsklinikum Bonn

Prof. Dr. med. Dieter Kabelitz
Institut für Immunologie
Universität Kiel

Dr. David Levens
NIH Bethesda, USA

Prof. Dr. med. Wilfried Roth
Institut für Pathologie der
Universität Heidelberg
und DKFZ

Dr. Esta Sterneck
National Institutes of Health
Bethesda, USA

Prof. Dr. Oliver Keppler
Institut für Medizinische Mikrobiologie
Goethe-Universität Frankfurt

Dr. Claudia Waskow
DFG Center for Regenerative Therapies
Regeneration in Hematopoiesis
TU Dresden

Dr. Pablo Menéndez Buján
Pfizer - Universidad de Granada
Granada, Spain

Dr. Jan Paul Medema
Center for Experimental Molecular Medicine
Academic Medical Center
Amsterdam

Prof. Dr. Oliver Keppler
Institut für Medizinische Mikrobiologie
Goethe-Universität Frankfurt

Prof. Dr. Itamar Barash
Institute of Animal Science
The Volcani Center
Bet-Dagan, Israel

PD Dr. Ekkehard Schütz
Chronix Biomedical and
Georg August University Göttingen

Dr. Katrin Hacke
University of California
Los Angeles

Dr. Carsten Watzl
Leibniz Research Centre for Working Environment and Human Factors - IfADo
Dortmund

Dr. Cornelius Miething
Memorial Sloan Kettering Cancer Center

Prof. Lisa Wiesmüller
Universität Ulm

Dr. Oliver Stehling
Universität Marburg

Dr. Bert Klebl
Dr. Peter Nussbaumer
Directors
Lead Discovery Center GmbH
Dortmund

PD Dr. Zoé Waibler
Paul-Ehrlich-Institut
Langen

Prof. Dr. Yihai Cao
Karolinska Institute
Stockholm

PD Dr. Frank Edenhofer
Institut für Rekonstruktive Neurobiologie, Universität Bonn
"Omnis cellula e cellula - Neue Wege der Reprogrammierung von Zellen"

PD Dr. Guido Posern
Max-Planck-Institut für Biochemie, Martinsried
"MALfunction in proliferation and cell motility"

Dr. Axel Schambach
Abteilung für Experimentelle Hämatologie, Medizinische Hochschule Hannover

Dr. Benedikt Berninger
Helmholtz-Zentrum München, German Research Center for Environment and Health
"Direct conversion of pericyte-derived cells of the adult brain into functional neurons"

PD Dr. Hildegard Büning
Center for Molecular Medicine Cologne (ZMMK), Universität Köln
"Tailoring viral vectors for cell and gene therapy"

Dr. Zsuzsanna Izsvák
Max-Delbrück-Center for Molecular Medicine, Berlin

PD Dr. Dirk Nettelbeck
Deutsches Krebsforschungszentrum und Universitätshautklinik Heidelberg
"Engineering adenoviruses for targeted and multimodal gene therapy and viral oncolysis"

Dr. Gerald Willimsky
Institut für Immunologie, Charíté, Berlin

Dr. Ralf Michael Zwacka
National University of Ireland (NUIG)
"Mesenchymal stem cells - friend and foe in cancer progression and therapy"

Prof. Dr. Volkhard Kempf
Institut für Med. Mikrobiologie
und Krankenhaushygiene
Klinikum der Goethe-Universität
Frankfurt

Dr. Matthias Drosten
Centro Nacional de Investigaciones Oncológicas, Madrid
"Critical aspects of Ras-signalling"

Dr. Anette Duensing
University of Pittsburgh Cancer Institute
"Oncogenic kinases and targeted therapies: lessons learned from gastro-intestinal stromal tumors (GIST)"

Dr. Irina Nazarenko
Karlsruhe Institute of Technology
"The role of intercellular communication by mean of extracellular vesicles in carcinogenesis"

Dr. Meike Vogler
MRC Toxicology Unit, Leicester, UK
"Targeting BCL-2 proteins for cancer therapy"

Dr. Pedro Medina
Yale University, New Haven, USA
"miRNAs and cancer"

Dr. Ulrich Elling
IMBA - Institute for Molecular Biotechnology
Wien, Österreich

Dr. Cyrus Khandanpour
Universität Essen

Dr. Tobias Berg
Dept. of Hematology
Universitätsklinikum Frankfurt

Prof. Dr. Keith Humphries
Terry Fox Laboratory
Vancouver, Canada

Sprecher:
Prof. Dr. Bernd Groner
Georg-Speyer-Haus, Frankfurt
Introduction: "Signal transducers and activators of transcription"

Prof. Dr. Lothar Hennighausen
NDDK, National Institutes of Health, Bethesda, USA
"Interpretation of cytokine signalling through the transcription factors Stat5a and Stat5b"

Prof. Dr. Hiroshi Wakao
Hokkaido University, Japan
"Constitutively active Stat5a and Stat5b promote adipogenesis"

Prof. Dr. Christine Watson
University of Cambridge, UK
"Stat3 controls lysosomal-mediatet cell death in vivo."

Prof. Dr. Jeffrey Rosen
Baylor College of Medicine, Houston, USA
"The epigenetic landscape of mammary gland development and functional differentiation"

Dr. Vida Vafaizadeh
Georg-Speyer-Haus, Frankfurt
"Stat5 assumes distinct functions in subsequent stages of mammary gland development and mammary tumor formation."

Prof. Dr. Valeria Poli
University of Turin, Italy
"A Stat3 mediated metabolic switch is involved in tumor transformation and Stat3 addiction."

Dr. Kamran Ghoreschi
Department of Dermatology
University of Tuebingen
"Jak inhibitors for the treatment of T cell mediated autoimmune diseases"

Dr. Jeanette Wood
S*BIO Pte Ltd., Singapore
"Pacritinib, a JAK2/FLT3 kinase inhibitor for the treatment of myeloid and lymphoid diseases"

Dr. Richard Moriggl
Ludwig Boltzmann Institute for Cancer Research, Vienna, Austria
"Stat5 is indispensable for the maintenance of bcr/abl positive leukemia"

Prof. Dr. Meinrad Busslinger
IMP - Research Institute of Molecular Pathology, Vienna, Austria
"Stat5 in B cell development and leukaemia"

Dr. Patrick Gunning
University of Hawaii Cancer Center
Honolulu, Hawaii, USA
"Targeting Stat3 in cancer: how successful are we?"

Kein Gastvortrag wg. Workshop

Prof. Dr. Andreas Diefenbach
Universitätsklinikum Freiburg

Dr. Ingram Iaccarino
Institute of Genetics and Biophysics (IGB)
CNR, Naples, Italy

Sprecher:
Prof. Dr. Florian Greten
Klinikum rechts der Isar, München
"Molecular analysis of inflammatory pathways during tumor initiation and progresssion"

Dr. Kathrin Maedler
Universität Bremen
"Anti-inflammatory targets: Rescue for diabetes"

Dr. Anton Meinhardt
MPI für Medizinische Forschung, Heidelberg
"The killer within: Bacterial suicide mechanisms for the collective good"

PD Dr. Christian Reinhardt
Uniklinik Köln
"Exploiting defects in the DNA-damage response for genetically-informed cancer therapy"

PD Dr. Nina Wettschurek
MPI für Herz- und Lungenforschung, Bad Nauheim
"New in vivo functions for the G-protein families Gq/G11 and G12/G13"

Prof. Dr. Bernd Kaina
Institut für Toxikologie
Universität Mainz

Dr. Martin Ringwald
The Jackson Laboratory
Bar Harbor, USA

Vorträge der Bewerber für die W3-Professur Tumorbiologie im GSH (Nachfolge Prof. Groner)

Vorträge der Bewerber für die W3-Professur Tumorbiologie im GSH (Nachfolge Prof. Groner)

Prof. Dr. Olivier Coqueret
Paul-Papin Cancer Center
Angers, France

Dr. Daniel Speidel
Children's Medical Research Institute
Cell Transformation Unit
Wentworthville, New South Wales
Australia

Prof. Dr. Rotraud Wieser
Medizinische Universität Wien

Prof. Dr. Rober B. Clarke
Paterson Institute for Cancer Research
University of Manchester
Manchester, UK

PD Dr. Christian Reinhardt
Universität Köln

Dr. Renate König
Paul-Ehrlich-Institut, Langen
und
Sanford-Burham Medical Research Institute, La Jolla
DER VORTRAG FÄLLT AUS!

Prof. Dr. med. Justus Duyster
Klinikum rechts der Isar
TU München

Dr. Ralf Kühn
Institute for Developmental Genetics
Helmholtz Center Munich

Prof. Dr. Andreas Burchert
Philipps-Universität Marburg
VORTRAG FINDET AM 09. JUNI STATT!

Dr. Ulrich Tschulena
Division Molecular Genome Analysis
DKFZ, Heidelberg

Veranstaltung des GRK 1172
Kein Gastvortrag

Dr. Pierre Debs
Molekulare Hämatologie
Universitätsklinikum Frankfurt

Dr. Claudia Scholl
Universitätsklinikum Ulm

Dr. Leo James
MRC, Cambridge, UK

Prof. Dr. Henk Stunnenberg
Radboud University Nijmegen Medical Centre

Dr. Cyril Fauriat
Centre de Recherche en Cancérologie de Marseille
Marseille, France

Prof. Dr. Alwin Krämer
DKFZ und Universitätsklinikum Heidelberg

Dr. Ahmet Ucar
MPI für biophysikalische Chemie
Göttingen

Prof. Dr. Karl Lenhard Rudolph
Institute of Molecular Medicine and Max-Planck-Research Department on Stem Cell Aging
Universität Ulm

Prof. Dr. Rober B. Clarke
Paterson Institute for Cancer Research
University of Manchester
Manchester, UK

SEMINAR CANCELLED! (18.11.10)

Prof. Dr. Christina Cardoso
Technische Universität Darmstadt

Prof. Dr. Christopher Baum
Dept. Experimental Oncology
Hannover Medical School
Hannover

Prof. Dr. Simone Fulda
Universitätsklinikum Frankfurt

Dr. Manfred Gossen
Berlin-Brandenburg Center for Regenerative Therapies
Berlin

Prof. Tarik Möröy
Université de Montréal
Montréal, Canada

Dr. med. Florian Greten
Klinikum Rechts der Isar
Technische Universität München

Dr. Michael Humbert
Dana Farber Cancer Institute
Harvard Medical School
Boston

Prof. Dr. Christoph Klein
Universität Regensburg

Dr. Zoltan Ivics
Max Delbrück Center for Molecular Medicine
Berlin

Prof. Dr. Jos Jonkers
The Netherlands Cancer Institute
Amsterdam

Dr. Niels Halama
NCT Heidelberg

Dr. Frank Winkler
Department of Neurology
University of Munich

Dr. Stefan Heinrichs
Dana-Farber Cancer Institute
Boston, USA

Prof. Dr. Peter Friedl
Department of Cell Biology
NCMLS, Radboud University Nijmegen Medical Centre
Nijmegen
The Netherlands

Prof. Dr. Michael Boutros
Deutsches Krebsforschungszentrum (DKFZ) und Universität Heidelberg

Dr. Stephen Gottschalk
Baylor College of Medicine
Houston, Texas

Dr. Christoph Walz
Universitätsmedizin Mannheim
Universität Heidelberg

Prof. Dr. Gerald Höfler
Institute of Pathology University of Graz

Prof. Dr. Dirk Jäger NCT Heidelberg

Dr. Kirsten Lauber Molekulare Gastroenterologie Innere Medizin II Universitätsklinikum Tübingen

Dr. Rupert Abele Dept. of Biochemistry, Biocenter University of Frankfurt

Dr. Björn Rotter
GenXPro GmbH
FIZ, Frankfurt

Dr. Juan Bueren, CIEMAT Madrid

Dr. Gertraud Robinson NIDDK/NIH, Bethesda, USA

Dr. Fritz Nolte
Institut für Immunologie
Universitätsklinikum Hamburg-Eppendorf

Dr. Frank Rosenbauer Max-Delbrück-Centrum für Molekulare Medizin (MDC), Berlin

Prof. Dr. Lothar Hennighausen
NIH/NIDDK
Bethesda, USA

Prof. Dr. Helga Bernhard
Klinikum Darmstadt

Dr. Erik Lubberts
University Medical Center Rotterdam

Prof. Dr. Axel Imhof
Adolf-Butenandt-Institut
München

Dr. Tomohiro Chiba
KEIO University, School of Medicine
Tokio, Japan

Prof. Dr. Karl-Klaus Conzelmann
Max-von-Pettenkofer Institut & Genzentrum der LMU

Prof. Dr. Alexander Steinle
Institut für molekulare Medizin
Universität Frankfurt

Dr. Kai Hilpert
KIT - Karlsruhe Institute of Technology

Dr. Richard Moriggl
Ludwig Boltzmann-Institute for Cancer Research
Wien

Schwerpunkttag

Welcome and Introduction
Keynote Lecture:
Ofer Mandelboim, Hebrew University, Hadassah Medical School,
Jerusalem, Israel
"Human and viral microRNAs controlling NK cell killing"

Klas Klärre
Karolinska Institutet, Stockholm, Sweden
"Natural killer cell recognition of missing self"

Werner Held
Ludwig Institute for Cancer Research,
Lausanne, Switzerland
Self-control of natural killer cells

Carsten Watzl
University of Heidelberg
"Integration of positive and negative signals inside NK cells"

Björn Onfelt
Karolinska Institutet, Stockholm, Sweden
"Novel approaches for imaging Natural Killer cell immune surveillance"

Christine Falk
University of Heidelberg
"The role of NK cell subsets in autoimmunity: lessons from the comparison between Rheumatoid Arthritis and Osteoarthritis"

Winfried Wels
Georg-Speyer-Haus, Frankfurt
"Retargeted killer cells for cellular cancer immunotherapy"

Hans-Gustav Ljunggren
Karolinska Institutet, Stockholm, Sweden
"Activation of human NK cells"

Evelyn Ullrich
Medical School Erlangen
"The role of NK cell subsets in antitumor therapy"

Lutz Uharek
Charité Berlin
"Clinical trials using allogeneic NK cells

Dr. Imre Berger
EMBL Grenoble

Prof. Dr. Friedrich Schüning
Vanderbilt University
Nashville, TN, USA

Prof. Dr. Carol Stocking
Heinrich-Pette-Institut, Hamburg

Dr. Andreas Herrlich
Whitehead Institute for Biomedical Research
Cambridge, USA

Dr. Ina Oehme
DKFZ, Heidelberg

Prof. Dr. Frank J. T. Staal
IHB, LUMC
Leiden, The Netherlands

12.00 - 13.00     Get together
13.00 - 13.10     Introduction (Jürgen Bereiter-Hahn, Frankfurt)
13.10 - 13.45     Amparo Acker-Palmer, Universität Frankurt
"Neurovascular guidance molecules as novel targets for tumor therapy"
13.45 - 14.20     Frank Bradke, MPI für Neurobiologie, München
"Intracellular mechanisms of axonal growth and regeneration"
14.20 - 14.55     Sven Diederichs, DKFZ Heidelberg   
"Argonaute proteins in microRNA biogenesis & RNA interference"
14.55 - 15.15     break
15.15 - 15.50     Marcus Fändrich, Halle a.d. Saale
"Targeting the structural basis in protein misfolding diseases"
15.50 - 16.25     Jan Münch, Universität Ulm
"Natural enhancers and inhibitors of HIV-1 infection"
16.25 - 17.00     Annika Vogt, Charite- Universität Berlin
"Targeting of skin antigen presenting cells - a rationale for nanoparticle-based transcutaneous vaccination"

Dr. Jeske Smink
Max-Delbrück Center for Molecular Medicine
Berlin

Thomas Schirrmann
TU Braunschweig

Prof. Dr. Roman Jerala
Department of Biotechnology
National Institute of Chemistry
Ljubljana, Slovenia

Dr. Rolf Thermann
EMBL, Heidelberg 

Dr. Rik Gijsbers
Universität Leuven

Dr. Ralph Vogelsang
Applied Biosystems, Genetics Analysis Systems

Dr. Elke Pogge von Strandmann
Universitätsklinikum Köln
Klinik I für Innere Medizin

Dr. Stefan Wiemann
DKFZ, Heidelberg

Dr. Susanne Sebens
Universitätsklinikum Schleswig-Holstein
Kiel

Prof. Dr. Andreas Radbruch
Deutsches Rheuma-Forschungszentrum Berlin (DRFZ)

Dr. Jörg Kirberg
Paul-Ehrlich-Institut

11.00 - 11.10
Martin Zörnig: Welcome
11.10 - 11.55 
Pascal Meier, The Breakthrough Toby Robins Breast Cancer Research Centre, Institute of Cancer Research, London
"Ub-mediated regulation of cell survival"
11.55 - 12.40 
Ivan Dikic, University Hospital Frankfurt
"NEMO binding to linear ubiquitin chains regulates NF-kB pathway"
12.40 - 14.00 Lunch
14.00 - 14.45
Krishnaraj Rajalingam, University Hospital Frankfurt
"The other side of IAPs: Role in RAF signalling and cell migration"
14.45 - 15.30
Volker Dötsch, University of Frankfurt
"The tails of p63"

Prof. Dr. Quentin Sattentau
Universität Oxford

Schwerpunkttag

Welcome and Introduction
Keynote Lecture:
Peter Becker, Adolf-Butenandt-Institut, München
"Vital fine-tuning of transcription: gene dosage compensation"

Rolf Marschalek
Institute for Pharmaceutical Biology, Frankfurt
"Purification of the leukemogenic AF4-MLL fusion protein and its putative function(s) for histone modifications"

Sandra Hake
Adolf-Butenandt-Institute, München
"How little changes can cause large effects: The tale of histone H3 variants and their post-translational modifications"

Coffee Break

Thorsten Berg
Max-Planck-Institute of Biochemistry, Martinsried
"Inhibition of transcription factors by small organic molecules"

Elisabeth Kowenz Leutz
Max-Delbrück-Center for Molecular Medicine, Berlin
"Regulation of CEBP activity by methylation"

Lunch Break
"Students meet Speakers" Postersession

Thorsten Heinzel
Center for Molecular Biomedicine, Jena
"Regulation of transcription factor activity by acetylation"

Jörn Lausen
Georg-Speyer-Haus, Frankfurt
"Transcription factor regulation by arginine methylation"

Guntram Suske
Institute for Molecular Biology and Tumor Research, Marburg
"Mechanisms of SUMO-dependent transcriptional gene silencing"

Coffee and Discussions

Dr. Berit Jungnickel
Helmholtz-Zentrum München
Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH)

Dr. Dirk Wolters
Ruhr-Universität Bochum

Dr. Meike Vogler
University of Leicester
UK

Dr. Marcus Krüger
Max-Planck-Institute for Heart and Lung Research
Bad Nauheim

Dr. Marisa Torres Arzayus
Dana Faber Cancer Institute
Boston

MR Gerd Mangel
Hessisches Ministerium für Wissenschaft und Kunst,
Wiesbaden

Prof. Dr. Lothar Hennighausen
NIDDK/NIH
Bethesda, USA

Prof. Dr. Emmanuel Wiertz
Universität Leiden

Dr. Marion Lohrum
Radboud University Nijmegen
The Netherlands

Dr. Krishnaraj Rajalingam
Institut für Biochemie II
Universitätsklinikum Frankfurt

Dr. Michael Rieger Helmholtz Zentrum München - German Research Center for Environmental Health